Handbook of Drug-Nutrient Interactions

Handbook of Drug-Nutrient Interactions, Second Edition is an essential new work that provides a scientific look behind many drug-nutrient interactions, examines their relevance, offers recommendations, and suggests research questions to be explored. In th

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NUTRITION

AND HEALTH Adrianne Bendich, PhD, FACN, SERIES EDITOR

For other titles published in this series, go to www.springer.com/series/7659

HANDBOOK OF DRUG-NUTRIENT INTERACTIONS Second Edition Edited by

JOSEPH I. BOULLATA, PharmD Associate Professor of Pharmacology & Therapeutics, University of Pennsylvania, School of Nursing, Philadelphia, PA, USA

and

VINCENT T. ARMENTI, MD, PhD Professor of Surgery, Professor of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA

Foreword by

GIL HARDY PhD, FRSC Professor of Pharmaceutical Nutrition, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand

Editors Joseph I. Boullata, PharmD Associate Professor of Pharmacology & Therapeutics University of Pennsylvania School of Nursing 418 Curie Blvd. Philadelphia PA 19104 USA

Vincent T. Armenti, MD, PhD Professor of Surgery Professor of Pathology, Anatomy, and Cell Biology Thomas Jefferson University 1025 Walnut St., Suite 605 Philadelphia, PA 19107 USA

Series Editor Adrianne Bendich, PhD GlaxoSmithKline Consumer Healthcare Parsippany, NJ

ISBN 978-1-60327-363-3 e-ISBN 978-1-60327-362-6 DOI 10.1007/978-1-60327-362-6 Library of Congress Control Number: 2009930756 # Humana Press, a part of Springer ScienceþBusiness Media, LLC 2010 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer ScienceþBusiness Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper springer.com

Dedication

This book is dedicated to our families who accepted with good humor the time required to work on the project. Joseph I. Boullata and Vincent T. Armenti

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Acknowledgement

We acknowledge the strong commitment of each of our authors to this project. Additionally, the ongoing support and encouragement from Adrianne Bendich for this topic and project has been invaluable. Finally, we acknowledge Richard Hruska and his staff at Humana Press for the administrative support of the project. Joseph I. Boullata and Vincent T. Armenti

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Series Editor Introduction

The Nutrition and Health Series of boo