Hormone Therapy of Acne Clinical and Experimental Principles
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Hormone Therapy of Acne Clinical and Experimental Principles
Springer-Verlag Wien New York
Doz. Dr. Doris Fanta University of Vienna Medical School, Vienna, Austria
Revised translation of "Akne. Klinische und experimentelle Grundlagen zur Hormontherapie" Wien-New York: Springer 1978
© 1978 by Springer-Verlag/Wien This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. © 1980 by Springer-Verlag/Wien Softcover reprint of the hardcover 1st edition 1980
The use of registered names, trademarks, etc. in the publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
With 25 Illustrations
Library of Congress Cataloging in Publication Data. Fanta, Doris. Hormone therapy of acne, clinical and experimental principles. Rev. translation of Akne, klinische und experimentelle Grundlagen zur Hormontherapie. Includes bibliographical references. 1. Acne-Chemotherapy. 2. Hormone therapy. 3. Dermatologic agents. I. Title. [DNLM: 1. Acne-Therapy. 2. Acne-Physiopathology. 3. HormonesTherapeutic use. 4. Sebaceous glands-Metabolism. WR430 F216a.] RL131.F3613.616.S'3.80-16942
ISBN-13:978-3-211-81586-1 DOl: 10.1007/978-3-7091-8590-2
e-ISBN-13:978-3-7091-8590-2
Foreword Is acne really just a cosmetically disturbing skin disorder of no pathologic significance? As far as the dermatologist is concerned, the answer to this question must be a definite no. The outpatient departments of dermatologic clinics and practices have a daily quota of young people who are distressed by acne eruptions and discouraged after futile self-therapy with various cosmetics. For them, this disfiguring skin disorder is a very serious disease, and they expect help and a cure from the physician. The appearance of the facial skin is important in interpersonal relations-in the private, social, and occupational spheres. Therefore it would be wrong to dismiss acne as an unpleasant symptom of puberty and to placate the patient during this phase of life with "pseudotherapy" . Several years ago Dr. Fanta turned her medical and scientific interest to the various problems of acne and founded her own outpatient department for acne at the Second Dermatological Clinic of the University of Vienna. Continuous confrontation with the numerous contradictions and inconsistencies of conventional acne therapy prompted Dr. Fanta to perform her own experimental and clinico-therapeutic studies to extend our knowledge about the pathomechanism of this disease. These studies have led to a number of significant publications-among them her work on the influence of hormones on acne, biochemical studies on the behaviour of skin lipids in this dermatosis, and important findings clarifying the mode of action of benzoyl peroxide. Many patient
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