Human Cell Transformation Advances in Cell Models for the Study of C
This book, part contributed volume, part proceedings, discusses state-of-the-art advances on human cell transformation in cell models for the study of cancer and aging. Several of the chapters are from the Human Cell Transformation: Advances in Cell Model
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Johng S. Rhim Anatoly Dritschilo Richard Kremer Editors
Human Cell Transformation Advances in Cell Models for the Study of Cancer and Aging
Advances in Experimental Medicine and Biology Volume 1164 Editorial Board: IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, PA, USA RODOLFO PAOLETTI, University of Milan, Milan, Italy NIMA REZAEI, Tehran University of Medical Sciences, Children’s Medical Center Hospital, Tehran, Iran
More information about this series at http://www.springer.com/series/5584
Johng S. Rhim • Anatoly Dritschilo Richard Kremer Editors
Human Cell Transformation Advances in Cell Models for the Study of Cancer and Aging
Editors Johng S. Rhim Department of Surgery Uniformed Services University of the Health Sciences Bethesda, MD, USA
Anatoly Dritschilo Georgetown University Medical Center Washington, DC, USA
Richard Kremer Department of Medicine McGill University Health Centre Montréal, QC, Canada
ISSN 0065-2598 ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-3-030-22253-6 ISBN 978-3-030-22254-3 (eBook) https://doi.org/10.1007/978-3-030-22254-3 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
The role of carcinogenic agents in the development of human cancer is defined using a variety of human cells as experimental model systems. Therefore, the study of human cell transformation in culture by carcinogenic agents is of particular importance for understanding the cellular and molecular mechanisms underlying human carcinogenesis.
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