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ORIGINAL ARTICLE

Identification of Novel Candidate Biomarkers for Oral Squamous Cell Carcinoma Based on Whole Gene Expression Profiling Sudaporn Kengkarn 1 & Songsak Petmitr 1 & Usa Boonyuen 1 & Onrapak Reamtong 1 & Sopee Poomsawat 2 & Sirima Sanguansin 3 Received: 25 November 2019 / Revised: 23 April 2020 / Accepted: 20 May 2020 # Arányi Lajos Foundation 2020

Abstract This study aimed to determine the whole gene expression profiles and to ascertain potential biomarkers for 22 oral squamous cell carcinoma (OSCC) among Thai patients using the Illumina Human HT-12, V4.0 Expression BeadChip array. Result indicated 2,724 differential expressed genes composed of 1,560 up-regulated and 1,164 down-regulated genes (unpaired t-test, p-value

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