Impact of concomitant peripheral artery disease on contrast-induced acute kidney injury and mortality in patients with a

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ORIGINAL ARTICLE

Impact of concomitant peripheral artery disease on contrast‑induced acute kidney injury and mortality in patients with acute coronary syndrome after percutaneous coronary intervention Takuya Nakahashi1 · Hayato Tada2 · Kenji Sakata2 · Yohei Yakuta3 · Taiji Yoshida3 · Yoshihiro Tanaka2 · Akihiro Nomura2 · Hidenobu Terai3 · Yuki Horita3 · Masatoshi Ikeda3 · Masanobu Namura3 · Masayuki Takamura2 · Masa‑aki Kawashiri2 Received: 20 January 2020 / Accepted: 17 April 2020 © Springer Japan KK, part of Springer Nature 2020

Abstract Subclinical peripheral artery disease (PAD) might be associated with pathophysiology of contrast-induced acute kidney injury (CI-AKI). We hypothesized that concomitant PAD in patients with the acute coronary syndrome (ACS) would represent a high-risk subgroup with a greater incidence of CI-AKI, both of which lead to higher mortality after percutaneous coronary intervention (PCI). Six hundred and seventy-five consecutive patients with ACS who underwent PCI and examination of ankle-brachial index (ABI) were analyzed retrospectively. The presence of PAD was defined as an ABI