Impact of Preoperative Cholangitis on Short-term Outcomes Among Patients Undergoing Liver Resection

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ORIGINAL ARTICLE

Impact of Preoperative Cholangitis on Short-term Outcomes Among Patients Undergoing Liver Resection Kota Sahara 1,2 & Katiuscha Merath 1 & J. Madison Hyer 1 & Anghela Z. Paredes 1 & Diamantis I. Tsilimigras 1 & Rittal Mehta 1 & Syeda A. Farooq 1 & Amika Moro 1 & Lu Wu 1 & Susan White 3 & Itaru Endo 2 & Timothy M. Pawlik 1,4 Received: 16 August 2019 / Accepted: 14 October 2019 # 2019 The Society for Surgery of the Alimentary Tract

Abstract Background The impact of preoperative cholangitis (PC) on perioperative outcomes among patients undergoing liver resection remains poorly defined. We sought to characterize the prevalence of PC among patients undergoing hepatectomy and define the impact of PC on postoperative outcomes. Methods Patients who underwent liver resection between 2013 and 2015 were identified using the Center for Medicare Services (CMS) 100% Limited Data Set (LDS) Standard Analytic Files (SAFs). Short-term outcomes after liver resection, stratified by the presence of PC, were examined. Subgroup analyses were performed to evaluate the relationship between the timing of liver resection relative to PC. Results Among 7392 patients undergoing liver resection, 251 patients (3.4%) experienced PC. Patients with PC were more likely to be male (59.0% vs. 50.6%) and to have a benign diagnosis (34.3% vs. 19.8%) compared with patients without PC (both p