Incorporation of natural assumption to deal with cancer

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REVIEW ARTICLE

Incorporation of natural assumption to deal with cancer Chenmala Karthika 1 & Raman Sureshkumar 1 Received: 9 May 2020 / Accepted: 29 October 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract The current state of the art for the use of natural ingredients for cancer therapy is by reviewing the publications and findings associated with cancer research with the employment of flavonoids. Cancer is the most furious disease making fear in the eyes of mankind. Though various treatment methods are prevalent, the patient’s choices are shifting from synthetic treatment strategy to the natural ones. The plant-based metabolites are used very often in our life as a food additive and also as a medicine for primary health care. The safety profile and its efficacy add on advantage for the incorporation of the natural products separately or in combination as a remedy for cancer. Flavonoids, the plant-based metabolites are proven for their anti-inflammatory, anti-oxidant, and anti-cancer properties. Their chemotherapeutic and chemosensitizing power had made it interesting for the researchers to dig more on the health benefits of the flavonoids and incorporating it in a holistic approach, with its natural benefits to relieve the pain and the symptoms of the patient suffering from various medical conditions. The predominant approach for the management of cancer is by following safe and effective treatment modality. In this review, we mentioned the benefits of the flavonoids for the management of various cancers and its potency as a chemotherapeutic agent and as the chemosensitizer. Our mother nature had given remedies to cure various diseases in both human beings and animals by it; we just need to find out the sources and access to them. Keywords Chemotherapy . Multidrug resistance . Cancer treatment . Dietary foods . Flavonoids . Epidemiological studies

Introduction Cancer is caused by the uninhibited proliferation of the cells in the body. The introduction of fast food and unhealthy living habits increased the risk of cancer in this generation. The death rates are high and the survival rates are low for the patients who are identified with cancer in the last stage or Duke E stage. The diagnosis at this stage and the recurrence are the major reasons behind the therapeutic failure with the aid of the current approaches. Though various treatment methods are available, the use of natural ingredients for the treatment of cancer and various ailments is coming forward as a new trend because of its health benefits and non-toxic action. The uses of the natural ingredients are safe while considering the patient’s point of view and also to our mother earth. The waste materials after the production using natural products will not Responsible Editor: Lotfi Aleya * Raman Sureshkumar [email protected] 1

Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Nilgiris, Tamil Nadu, India

produce any harmful effects to the environment. This nonto