Infections and the Rheumatic Diseases

This book provides a comprehensive and up-to-date review of the basic and clinical aspects of infections and infectious processes that trigger or aggravate a variety of autoimmune and inflammatory musculoskeletal disorders. It delivers a timely update on

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Clinical InfectionsMedicine and the Covertemplate Rheumatic Diseases Subtitle for Clinical Medicine Covers T3_HB Second Edition

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Infections and the Rheumatic Diseases

Luis R. Espinoza Editor

Infections and the Rheumatic Diseases

Editor Luis R. Espinoza LSU Health Sciences at New Orleans Louisiana State University New Orleans, LA USA

ISBN 978-3-030-23310-5    ISBN 978-3-030-23311-2 (eBook) https://doi.org/10.1007/978-3-030-23311-2 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Foreword

The intersection of infectious diseases and rheumatology has progressed at a torrid rate over the past generation; thus, it is timely to welcome such a comprehensive book as Infections and the Rheumatic Diseases for both the practitioner and for those engaged in basic and clinical investigations in this evolving field. Conceptually, the field can be viewed as a triptych painting, whereby in one frame infections are viewed as the etiology of rheumatic signs, symptoms, or as the cause of distinct nosological diseases (e.g., hepatitis C-associated cryoglobulinemia). Alternatively, in another frame, infections may represent formidable comorbidities to be dealt with by clinicians attempting to balance immunosuppressive regimens with a wide variety of chronic latent or persistent infections (e.g., hepatitis B or HIV). The final frame of this exhibit is the growing field of infections induced by our immune-based therapies which range from merely the frequent and mild ubiquitous respiratory infections observed to be increased in virtually every clinical trial of biologic and non-biologic disease-modifying antirheumatic drugs (DMARDs) or the increasingly recognize