Inflammation, Aging, and Oxidative Stress
The book describes the major degenerative processes and pathologies exacerbated by senescence and how they can be alleviated through retardation of cellular aging. Topics discussed include neurodegenerative disease, protein oxidation, cerebrovascular dise
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Stephen C. Bondy Arezoo Campbell Editors
Inflammation, Aging, and Oxidative Stress
Oxidative Stress in Applied Basic Research and Clinical Practice
Editor-in-Chief Donald Armstrong
More information about this series at http://www.springer.com/series/8145
Note from the Editor-in-Chief All books in this series illustrate point-of-care testing and critically evaluate the potential of antioxidant supplementation in various medical disorders associated with oxidative stress. Future volumes will be updated as warranted by emerging new technology, or from studies reporting clinical trials. Donald Armstrong Editor-in-Chief
Stephen C. Bondy • Arezoo Campbell Editors
Inflammation, Aging, and Oxidative Stress
Editors Stephen C. Bondy Department of Medicine Center for Occupational and Environmental Health University of California Irvine, CA, USA
Arezoo Campbell Department of Pharmaceutical Sciences College of Pharmacy Western University of Health Sciences Pomona, CA, USA
ISSN 2197-7224 ISSN 2197-7232 (electronic) Oxidative Stress in Applied Basic Research and Clinical Practice ISBN 978-3-319-33484-4 ISBN 978-3-319-33486-8 (eBook) DOI 10.1007/978-3-319-33486-8 Library of Congress Control Number: 2016949388 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
Preface
Aging carries inherent risk upon which distinct diseases are superimposed. Normal physiological processes tend to develop pathological aspects, which further disrupt declining tissue function. These age-related diseases often exaggerate the typical cellular changes accumulating with time, which are associated with senescence. For this reason, there has been a gradual merging of concepts regarding normal aging and specific disorders. The aim of this book is to describe this interface, emphasizing two
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