Introduction to Translational Cardiovascular Research

The term “Translational Research” reflects today’s integration of basic research (“bench”) findings with the clinical practice of medicine, and in a wider scope the application of results from the individual patient (“bedside”) to entire populations for t

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Introduction to Translational Cardiovascular Research

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Introduction to Translational Cardiovascular Research

Dennis V. Cokkinos Editor

Introduction to Translational Cardiovascular Research

Editor Dennis V. Cokkinos, MD, FESC Biomedical Research Foundation Academy of Athens Athens Greece

ISBN 978-3-319-08797-9 ISBN 978-3-319-08798-6 DOI 10.1007/978-3-319-08798-6 Springer Cham Heidelberg New York Dordrecht London

(eBook)

Library of Congress Control Number: 2014954073 © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher's location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

All the authors dedicate this book to our families and our students. The editor (DVC) additionally dedicates it to his wife Vana, in translation

Foreword

It is with great pleasure that I write this foreword for two reasons: First, the concept of this book emerged from two seminars held in our institution with the same title, Introduction to Translational Cardiovascular Research, with Professor Dennis V. Cokkinos, Director of the Heart and Vessel Department, who is also the Editor of this book as the course organizer, and Professor Evangelia Kranias, Director of Molecular Biology, Hanna Professor of Cardiology, Chair, Department of Pharmacology and Cell Biophysics, University of Cincinnati Co