Iohexol
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Transient cortical blindness: case report A 56-year-old man developed transient cortical blindness (TCB) after an elective coronary angiography (CAG) using iohexol 300mL [Omnipaque 350 mg/mL; route not stated]. The man underwent successful catheterisation of coronary artery vessels, but prolonged catheterisation of the left and right internal mammary arteries due to technical difficulties; iohexol was used as contrast agent during the CAG procedure. He reported bilateral vision loss 1 hour after the procedure, and cranial CT scans neither revealed any cerebral haemorrhage or ischaemia, nor bilateral contrast enhancement in the occipital lobes. The man underwent hydration with sodium chloride, and his vision returned 24 hours after CAG, and fully recovered within 48 hours. He had no residual blindness at 6 months’ follow-up. Author comment: "[W]e report our experience of a patient with TCB developed one hour after CAG and resolved spontaneously at 24 hour after the procedure. . . Patients underwent coronary artery bypass graft operation, especially IMA grafts, have seperate risk factor for developing TCB." Tuncer M, et al. Transient cortical blindness can also be seen in the absence of contrast enhancement at computed tomography scan after coronary angiography. Pakistan Journal of Medical Sciences 28: 540-542, No. 3, Apr-Jun 2012 803075190 Turkey
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Reactions 11 Aug 2012 No. 1414
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