Kawasaki Disease Current Understanding of the Mechanism and Evidence
This book provides the most up-to-date information on the clinical research into and medical management of Kawasaki Disease, and opens the door for new pathological insights. Its nearly 50 sections cover basic research, genetic backgrounds, bacterial and
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Kawasaki Disease Current Understanding of the Mechanism and Evidence-Based Treatment
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Kawasaki Disease
Ben Tsutomu Saji • Jane W. Newburger • Jane C. Burns • Masato Takahashi Editors
Kawasaki Disease Current Understanding of the Mechanism and Evidence-Based Treatment
Editors Ben Tsutomu Saji Advanced and Integrated Cardiovascular Research Course in the Young and Adolescence Toho University Tokyo, Japan Jane C. Burns Department of Pediatrics, Rady Children’s Hospital University of California San Diego School of Medicine La Jolla, USA
Jane W. Newburger Harvard Medical School, Department of Cardiology Boston Children’s Hospital Boston, USA Masato Takahashi Heart Center Seattle Children’s Hospital Seattle, USA
ISBN 978-4-431-56037-1 ISBN 978-4-431-56039-5 DOI 10.1007/978-4-431-56039-5
(eBook)
Library of Congress Control Number: 2016940912 © Springer Japan 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Japan KK
Dedication It was almost 45 years ago, in November 1969, when I met Dr. Kawasaki. I was working in the Department of Pathology at the Japanese Red Cross Medical Center (formerly: Red Cross Central Hospital). I had little knowledge of Kawasaki disease but suddenly became interested when I conducted autopsies of Kawasaki disease patients. I have been deeply involved with this mysterious disease ever since. Dr. Kawasaki is a great doctor, who proved from daily observations of patients that Kawasaki disease has very peculiar features. He has always been straightforward, like an innocent child, and I have been on friendly terms with this “Extraordinary child” for a long time. Admiring the Glory of Dr. Tomisaku Kawasaki and his family. Shiro Naoe, M.D., Ph.D. Professor Emeritus Toho University ***
I feel greatly privileged to have the opportunity to write this dedication to honor Dr. Tomisaku Kawasaki, my dear friend for the past 31 years. Tomi
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