Leprosy A Practical Guide
In this book, the reader is guided through a modern diagnostic work-up and classification of leprosy, with discussion of the results of physical examination (interpretation of the primary skin lesion and clinical features of peripheral neuropathies), labo
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Enrico Nunzi Cesare Massone •
Editors
Leprosy A Practical Guide Foreword by Marcos Virmond
123
Enrico Nunzi Universidad Tecnica Particular de Loja Loja Ecuador
ISBN 978-88-470-2375-8 DOI 10.1007/978-88-470-2376-5
Cesare Massone Department of Dermatology Medical University of Graz, Graz Austria
e-ISBN 978-88-470-2376-5
Springer Milan Heidelberg New York Dordrecht London Library of Congress Control Number: 2012931859 Ó Springer-Verlag Italia 2012 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the Italian Copyright Law in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the Italian Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover design: eStudio Calamar S.L. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
To Raoul Follereau who has shown the way to many
Foreword
When the advances in medical science are taken into consideration, it is amazing to see that a millenary old disease such as leprosy reaches the twenty first Century, and is still affecting large proportions of the world population. On the one hand, it is an intriguing disease with many obscure pathophysiologic mechanisms still to be understood, on the other hand, after a boom of concern in the turn to the 20th century, the discovery of Dapsone treatment in the 1940’s and the adoption of WHO-multidrug therapy in the 1980’s, leprosy has gradually become a less important topic in medical schools and a non- issue in the minds of health authorities. Indeed, in the last decades due to worldwide BCG vaccination, to the use of multidrug therapy and improvements in patient care during the elimination campaign, the number of cases reduced worldwide and the epidemiologic features of the disease seem to change. However, it is clear that the disease has not been eradicated. Leprosy continues to be a major problem in many countries, not only because of the presence of a continued transmission of the disease but also because of the continued onset of disabilities and deformities that lead to patients suffering and to stigma and social and economical burden. In contrast to the potential resolution of the leprosy endemic envisaged in the pr
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