Lusutrombopag is effective and safe in patients with chronic liver disease and severe thrombocytopenia: a multicenter re
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RESEARCH ARTICLE
Open Access
Lusutrombopag is effective and safe in patients with chronic liver disease and severe thrombocytopenia: a multicenter retrospective study Hiroaki Nomoto1, Naoki Morimoto1, Kouichi Miura1*, Shunji Watanabe1, Yoshinari Takaoka1, Hiroshi Maeda1, Takahiro Sasaki2, Yohei Koyashiki2, Hidekazu Kurata3, Norikatsu Numao4, Norio Isoda1 and Hironori Yamamoto1
Abstract Background: Chronic liver disease (CLD) is often complicated by severe thrombocytopenia (platelet count 50,000/µL at baseline: the proportions of patients who did not require platelet transfusion were 84–96%, which might be overestimated. Methods: The efficacy and safety of lusutrombopag were retrospectively investigated in CLD patients with platelet count of 50,000/µL. However, lusutrombopag is effective and safe for CLD patients with a platelet count of
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