Severe Fever with Thrombocytopenia Syndrome
This book presents the latest knowledge on all aspects of severe fever with thrombocytopenia syndrome (SFTS), an emerging infectious disease endemic to China, South Korea, and Japan that is caused by a bunyavirus first discovered in 2011, widely referred
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Severe Fever with Thrombocytopenia Syndrome
Severe Fever with Thrombocytopenia Syndrome
Masayuki Saijo Editor
Severe Fever with Thrombocytopenia Syndrome
Editor Masayuki Saijo Department of Virology 1 National Institute of Infectious Diseases Tokyo, Japan
ISBN 978-981-13-9561-1 ISBN 978-981-13-9562-8 (eBook) https://doi.org/10.1007/978-981-13-9562-8 © Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Preface
Severe fever with thrombocytopenia syndrome (SFTS) was reported to be a novel bunyavirus infection by the Chinese scientists in 2011. SFTS is a tick-borne virus infection with high case fatality, and its vectors playing a role in transmitting the causative agent, SFTS virus (SFTSV), are Haemaphysalis longicornis and others. To tell the truth, I could not imagine that SFTS was endemic to Japan, when I received the information on the discovery of SFTS in China, even though I knew the evidence that Haemaphysalis longicornis was prevalent in Japan. In autumn, 2012, a woman aged 50s died of multiorgan failure with unknown etiologies. She was retrospectively diagnosed as having SFTS by isolation of SFTSV from the serum specimen and identification of SFTSV antigen in the tissue specimens through the postmortem examination in Japan. The discovery of SFTS patient in Japan indicated that SFTS was also endemic not only to China but also to Japan. SFTS patient was also identified in South Korea as well. SFTSV is circulating in nature in some regions of mainland China, Korean peninsula, and Japan through the lifecycle between mammals and some species of ticks. The evidence indicates that SFTS has occurred since the past an
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