Magnetic Resonance (MR) Imaging of the cardiac venous system and MR-guided intubation of the coronary sinus in swine: a
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Magnetic Resonance (MR) Imaging of the cardiac venous system and MR-guided intubation of the coronary sinus in swine: a feasibility-study Mirja Neizel*1, Nils Kraemer2, Jan Balzer1, Bernhard Schnackenburg3, Malte Kelm1, Rolf W Guenther2, Harald P Kuehl2 and Gabriele A Krombach2 Address: 1University Hospital Duesseldorf, Duesseldorf, Germany, 2University Hospital Aachen, Duesseldorf, Germany and 3Philips Medical Systems, Hamburg, Germany * Corresponding author
from 13th Annual SCMR Scientific Sessions Phoenix, AZ, USA. 21-24 January 2010 Published: 21 January 2010 Journal of Cardiovascular Magnetic Resonance 2010, 12(Suppl 1):O23
doi:10.1186/1532-429X-12-S1-O23
Abstracts of the 13th Annual SCMR Scientific Sessions - 2010
Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-infoThis abstract is available from: http://jcmr-online.com/content/12/S1/O23 © 2010 Neizel et al; licensee BioMed Central Ltd.
Introduction Procedures like cardiac resynchronization therapy (CRT) or percutanous transcatheter mitral annuloplasty where improved 3-dimensional knowledge about cardiac and cardiac vein anatomy is needed may benefit from magnetic resonance (MR)-guidance.
1.25 ms, flip angle 45°, slice thickness 8 mm, matrix 128 × 128 reconstructed to 256 × 256 using zero-filling. Planning of the image planes, especially for the coronary sinus, were performed with the help of the wholeheart acquisition. Time needed was measured for MR-guided intubation of the CVS and compared to the time needed for fluoroscopy guided intubation of the CVS.
Purpose The aim of this study was to visualize the coronary sinus using MR imaging and to demonstrate the feasibility of MR-guided intubation of the cardiac venous system (CVS) in swine.
Methods 6 pigs were investigated. All experiments were performed using an interventional 1.5 Tesla MRI system. The CVS was visualized using an inversion-recovery navigatorgated whole-heart steady-state free precession sequence after administration of Gd-BOPTA contrast agent (130150 slices, voxel size 1.2 × 1.2 × 1.8 mm3, TR/TE 6.4/3.2, flip angle 85°. Parallel imaging was used with a SENSEfactor of 2. The coronary sinus was then intubated under MR-guidance with a passive MR-compatible guidewire modified by incorporation of iron oxide markers for improved visualization and a non-braded Cobra-catheter. MR-guided interventions were monitored using a steadystate free precession real-time imaging sequence. Parameters of the real-time imaging sequence were TR/TE = 2.5/
Results The CVS could be visualized in all animals (100%). The diameter of the ostium of the coronary sinus was 7.6 ± 0.75 mm measured using the inversion-recovery 3-dimensional steady-state free-precession balanced wholeheart sequence. Intubation of the coronary sinus and its site branches was also feasible in all cases. Time spent for MRguided intubation of the CVS was comparable to time
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