mGLU Receptors
Metabotropic glutamate receptors (mGluRs) are members of the group C family of G-protein-coupled receptors. Eight different mGlu subtypes have been identified and classified into three groups based on amino acid sequence similarity, agonist pharmacology,
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Richard Teke Ngomba Giuseppe Di Giovanni Giuseppe Battaglia Ferdinando Nicoletti Editors
mGLU Receptors
The Receptors
Volume 31
Series Editor Giuseppe di Giovanni Department of Physiology & Biochemistry Faculty of Medicine and Surgery University of Malta Malta, Italy
The Receptors book Series, founded in the 1980’s, is a broad-based and wellrespected series on all aspects of receptor neurophysiology. The series presents published volumes that comprehensively review neural receptors for a specific hormone or neurotransmitter by invited leading specialists. Particular attention is paid to in-depth studies of receptors’ role in health and neuropathological processes. Recent volumes in the series cover chemical, physical, modeling, biological, pharmacological, anatomical aspects and drug discovery regarding different receptors. All books in this series have, with a rigorous editing, a strong reference value and provide essential up-to-date resources for neuroscience researchers, lecturers, students and pharmaceutical research.
More information about this series at http://www.springer.com/series/7668
Richard Teke Ngomba • Giuseppe Di Giovanni Giuseppe Battaglia • Ferdinando Nicoletti Editors
mGLU Receptors
Editors Richard Teke Ngomba Neuropharmacology Unit I.N.M. Neuromed I.N.M. Neuromed Pozzilli, Isernia, Italy
Giuseppe Di Giovanni Department of Physiology and Biochemistry University of Malta Malta, Italy
Giuseppe Battaglia Neuropharmacology Unit I.N.M. Neuromed Pozzilli, Isernia, Italy
Ferdinando Nicoletti Dipartimento di Fisiologia Umana Università di Roma Roma, Italy
The Receptors ISBN 978-3-319-56168-4 ISBN 978-3-319-56170-7 (eBook) DOI 10.1007/978-3-319-56170-7 Library of Congress Control Number: 2017948653 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Humana
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