Endocrinology

DDDDDDDDDDDD Effective management logically follows accurate diagnosis. Such logic often is difficult to apply in practice. Absolute diagnostic accuracy may not be possible, particularly in the field of primary care, when management has to be on analysis

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MANAGEMENT OF COMMON DlSEASES IN FAMILY PRACTICE

DDDDDDDDDDDD Series Editors: J. Fry and M. Lancaster-Smith

ENDOCRINOLOGY DDDDDDDDDDDD P. Marsden, BSe, MD, FRCP Consultant Physician, Greenwich District Hospital and

A. G. McCuliagh, BA, MB, BCh General Practitioner, Lakeside Health Centre, Thamesmead

Springer-Science+Business Media, B.V.

British Library Cataloguing in Publication Data Marsden, Philip, 1941Endocrinology. - (Management of common diseases in family practice) 1. Endocrine glands 2. Diseases I. Title 11. McCuliagh, A.G. III. Series 616.4 RC648 ISBN 978-94-010-9302-6 ISBN 978-94-010-9300-2 (eBook) DOI 10.1007/978-94-010-9300-2 Copyright © 1985 P. Marsden and A. G. McCullagh Softcover reprint of the hardcover 1st edition 1985 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from the publishers. Typeset and Printed by UPS Blackburn, 76-78 Northgate, Blackburn, Lancashire.

Contents

000000000000 Series Editors' Foreword

vii

1.

Introduction Nature of endocrine disease

1

2.

The Pancreas Diabetes mellitus - prevalence, aetiology, diagnosis. Diabetic Care: clinical features: management. The new NIDD diabetic: diet, insulin therapy, Problems. The non-insulin dependent diabetic. Who needs insulin? Complications. Summary.

7

3

Thyroid Disease Goitre. Hypothyroidism. Hyperthyroidism.

39

4

The Parathyroid Gland and Calcium Metabolism The physiology of bone production: Rickets and osteomalcia. Hyperparathyroidism: hypofunction: how to measure the serum calcium: summary. Osteoporosis: Paget's disease of bone.

77

v

5

Endocrine Diseases of the Ovary and Breast 95 Hypogonadism in the female. Puberty. Infertility. Hirsutism and virilism. Disorders of sexual differentiation. Endocrine effects of ovarian tumours. Endocrine disorders of the breast: painful breasts (chronic mastitis): galactorrhoea: gynaecomastia.

6.

135 The Testis Hypogonadism: the infertile male: the impotent male: anatomical disorders.

7.

Disorders of the Pituitary 147 The pituitary gland. Hypopituitarism: diabetes insipidus. Syndromes resulting from excess secretion of pituitary hormones: acromegaly: Cushing's disease: Hyperprolactinaemia. Space-occupying lesion in the pituitary fossa.

8.

Disorders of the Adrenal Gland 169 Function. Hypofunction of the adrenal cortex: Addison's disease: summary. Hyperfunction of the adrenal cortex: Cushing's syndrome: hyperaldo steronism. Hyperfunction and abnormalities of adrenal androgens. Congenital adrenal hyperplasia. Disorders of the adrenal medulla. Index

185

vi

Series Editors' Foreword

DDDDDDDDDDDD Effective management logically follows accurate diagnosis. Such logic often is difficult to apply in practice. Absolute diagnostic accuracy may not be possible, particularly in the field of primary care, when management has to be on analysis of symptoms and on knowledge of the individual patient and family. T