Minimum clinical important difference for resilience scale specific to cancer: a prospective analysis
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RESEARCH
Minimum clinical important difference for resilience scale specific to cancer: a prospective analysis Zeng Jie Ye1*† , Zhang Zhang2†, Ying Tang3, Jian Liang4, Xiao Ying Zhang5, Guang Yun Hu6, Zhe Sun7, Mu Zi Liang8 and Yuan Liang Yu9
Abstract Background: The minimum clinical important differences (MCIDs) of resilience instruments in patients with cancer have not been comprehensively described.This study was designed to evaluate MCIDs of 10-item and 25-item resilience scales specific to cancer (RS-SC-10 and RS-SC-25). Methods: From June 2015 to December 2018, RS-SCs were longitudinally measured in 765 patients with different cancer diagnoses at baseline (T0) and 3 months later (T1). The EORTC QLQ-C30, Connor-Davidson Resilience Scale, Hospital Anxiety and Depression Scale, and Allostatic Load Index were measured concurrently as anchors. Anchorbased methods (linear regression, within-group), distribution-based methods(within-group), and receiver operating characteristic curves (ROCs, within-subject) were performed to evaluate the MCIDs. Results: 623 of 765 (84.1%) patients had paired RS-SCs scores. Moderate correlations were identified between the change in RS-SCs and change in anchors (r = 0.38–0.44, all p
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