Mitochondria in Health and in Sickness
Besides bringing together researchers and clinicians from various disciplines to share their scope of research on the seminal role of mitochondria in human disease, this original volume of the book has a broader appeal by exploring the health and disease
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Andrea Urbani Mohan Babu Editors
Mitochondria in Health and in Sickness
Advances in Experimental Medicine and Biology Volume 1158
Editorial Board: IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, PA, USA RODOLFO PAOLETTI, University of Milan, Milan, Italy NIMA REZAEI, Tehran University of Medical Sciences, Children’s Medical Center Hospital, Tehran, Iran
More information about this series at http://www.springer.com/series/5584
Andrea Urbani • Mohan Babu Editors
Mitochondria in Health and in Sickness
Editors Andrea Urbani Institute of Biochemistry and Clinical Biochemistry Università Cattolica del Sacro Cuore Rome, Italy
Mohan Babu Department of Biochemistry University of Regina Regina, Saskatchewan, Canada
Fondazione Policlinico Universitario A. Gemelli – IRCCS Rome, Italy
ISSN 0065-2598 ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-981-13-8366-3 ISBN 978-981-13-8367-0 (eBook) https://doi.org/10.1007/978-981-13-8367-0 © Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Contents
1 Mitochondrial Metabolism in Cancer. A Tangled Topic. Which Role for Proteomics? �������������������������������������������������������� 1 Patrizia Bottoni and Roberto Scatena 2 Mitochondrial Proteins in the Development of Parkinson’s Disease ������������������������������������������������������������������ 17 Mara Zilocchi, Mauro Fasano, and Tiziana Alberio 3 Role of Mitochondria in Host-Pathogen Interaction��������������
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