RNA Metabolism in Mitochondria

This volume focuses on mitochondrial RNA metabolism, emphasizing recent discoveries and technological advances in this fast moving area that increase our understanding of mitochondrial gene function. Topics addressed include the interplay of mitochondria

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Jorge Cruz-Reyes · Michael W. Gray Editors

RNA Metabolism in Mitochondria

Nucleic Acids and Molecular Biology Volume 34

Series Editor Allen W. Nicholson Philadelphia, PA, USA

More information about this series at http://www.springer.com/series/881

Jorge Cruz-Reyes • Michael W. Gray Editors

RNA Metabolism in Mitochondria

Editors Jorge Cruz-Reyes Department of Biochemistry and Biophysics Texas A&M University College Station, Texas, USA

Michael W. Gray Department of Biochemistry and Molecular Biology, Centre for Comparative Genomics and Evolutionary Bioinformatics Dalhousie University Halifax, Nova Scotia, Canada

ISSN 0933-1891 ISSN 1869-2486 (electronic) Nucleic Acids and Molecular Biology ISBN 978-3-319-78189-1 ISBN 978-3-319-78190-7 (eBook) https://doi.org/10.1007/978-3-319-78190-7 Library of Congress Control Number: 2018944140 © Springer International Publishing AG, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by the registered company Springer International Publishing AG part of Springer Nature. The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

According to endosymbiont theory, mitochondria are the descendants of a once freeliving bacterial lineage, phylogenetically related to a specific bacterial group, the α-Proteobacteria. In essence, the mitochondrion may be regarded as a stripped-down and highly re-tailored bacterium. Although initially, in the evolving mitochondrion, gene expression would have been carried out by bacterial-type systems of transcription, posttranscriptional processing, and translation, these systems have been substantially altered during evolutionary transformation of endosymbiont to organelle: and differentially so, in various eukaryotic lineages. In particular, nucleus-encoded proteins, some of w