Mouse Development From Oocyte to Stem Cells

The mouse is a perfect model organism to study mammalian, and thus indirectly also human, embryology. Most scientific achievements that have had an important impact on the understanding of basic mechanisms governing embryo development in humans, originate

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Series Editors Dietmar Richter, Henri Tiedge

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Jacek Z. Kubiak Editor

Mouse Development From Oocyte to Stem Cells

Editor Jacek Z. Kubiak Institute of Genetics and Development of Rennes (IGDR) UMR 6290, CNRS/University Rennes 1 Faculty of Medicine, UEB, IFR 140 6290 Rennes Cedex France Series Editors Dietmar Richter Center for Molecular Neurobiology University Medical Center Hamburg-Eppendorf (UKE) University of Hamburg Hamburg Germany

Henri Tiedge The Robert F. Furchgott Center for Neural and Behavioral Science Department of Physiology and Pharmacology Department of Neurology SUNY Health Science Center at Brooklyn Brooklyn, NY, USA

ISSN 0080-1844 ISSN 1861-0412 (electronic) ISBN 978-3-642-30405-7 ISBN 978-3-642-30406-4 (eBook) DOI 10.1007/978-3-642-30406-4 Springer Heidelberg New York Dordrecht London Library of Congress Control Number: 2012945633 # Springer-Verlag Berlin Heidelberg 2012 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface

My purpose in preparing “Mouse Development. From Oocyte to Stem Cells” for the Springer series “Results and Problems in Cell Differentiation” was to create a comprehensive review of the current knowledge on the most popular mammalian model in developmental biology. Most scientific achievements that have had an i