Neuronal Development

Studies of simple and emerging systems have been undertaken to un­ derstand the processes by which a developing system unfolds, and to understand more completely the basis of the complexity of the fully formed structures. The nervous system has long been

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CURRENT TOPICS IN NEUROBIOLOGY Series Edi lor

Samuel H. Barondes Professor of Psychilliry School of Medicine Universihj of Cillifomill, Sml Diego Lil Jolla, Clllifomill

Tissue Culture of the Nervous System Edited by Gordon Sato Neuronal Recognition Edited by Samuel H. Barondes Pep tides in Neurobiology Edited by Harold Gainer Neuronal Development Edited by Nicholas C. Spitzer Neuroimmunology Edited by Jeremy Brockes

A continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediatedly upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.

Neuronal Development Edited by

Nicholas C. Spitzer University of California, San Diego La Jolla, California

PLENUM PRESS • NEW YORK AND LONDON

Library of Congress Cataloging in Publication Data Main entry under title: Neuronal development. (Current topics in neurobiology) Includes bibliographical references and index. 1. Developmental neurology. I. Spitzer, Nicholas C. II. Series. [DNLM: 1. Ner· vous system-Embryology. 2. Nervous system-Growth and development. WI CU82P v. 4/WL 0101 N493] 591.3'34 82-3693 QP363.5.N49 ISBN-13: 978-1-4684-1133-1 e-ISBN-13: 978-1-4684-1131-7 AACR2 DOl: 10.1007/978-1-4684-1131-7

© 1982 Plenum Press, New York Softcover reprint of the hardcover 1st edition 1982 A Division of Plenum Publishing Corporation 233 Spring Street, New York, N.Y. 10013 All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher

Contribu tors

KATE F. BARALD

Department of Anatomy and Cell Biology University of Michigan Medical School Ann Arbor, Michigan

DARWIN K. BERG

Department of Biology University of California, San Diego La Jolla, California

SETH S. BLAIR

Department of Molecular Biology University of California, Berkeley Berkeley, California

W. MAXWELL COWAN

Salk Institute for Biological Studies San Diego, California

JOHN S. EDWARDS

Department of Zoology University of Washington Seattle, Washington

THOMAS E. FINGER

Department of Anatomy University of Colorado Medical Center Denver, Colorado v

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Contributors

MURRAY S. FLASTER

Department of Biological Sciences Columbia University New York, New York

COREY S. GOODMAN

Department of Biological Sciences Stanford University Stanford, California

MARCUS JACOBSON

Department of Anatomy School of Medicine University of Utah Salt Lake City, Utah

PAUL C. LETOURNEAU

Department of Anatomy University of Minnesota Minneapolis, Minnesota

EDUARDO R. MACAGNO

Department of Biological Sciences Columbia University New York, New York

JOHN PALKA

Department of Zoology University of Washington Seattle, Washington

ROBERT S. SCHEHR

Department of Biological Sciences Columbia University New York, New York

GUNTHER S. STENT

Department of Molecular Biology University of California, Berkeley Berkeley, Cali