NeuroPET Positron Emission Tomography in Neuroscience and Clinical N
Positron emission tomography (PET) provides unbiased in vivo measurement of local tracer activity at very high sensitivity. This is a unique property unmatched by other imaging modalities. When PETwas introduced into medicine more than 25years ago, the fi
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Springer-Verlag Berlin Heidelberg Gm bH
K. Herholz- P. Herscovitch· W.-D. Heiss
NeuroPET Positron Emission Tomography in Neuroscience and Clinical Neurology
With 66 Figures and 11 Tables
,
Springer
Karl Herholz, Prof. Dr. W.-D. Heiss, Prof. Dr. Neurologische Universitatsklinik Max-Planck-Institut fur Neurologische Forschung Joseph-Stelzmann-Str.9 D-50931 Koln Germany
Peter Herscovitch, MD Chief, PET Imaging Section National Institutes of Health Clinical Center 10 Center Drive MSC 1180 Bethesda, MD 20892-1180 USA
Additional material to this book ean be downIoaded from http://extra5.springer.com. ISBN 978-3-642-62283-0 ISBN 978-3-642-18766-7 (eBook) DOI 10.1007/978-3-642-18766-7 Library of Congress Control Number: 2004105242 Dr. Herscovitch's work as author was performed outside the scope of his employment as a U. S. government employee. This work represents his personal and professional views and not necessarily those of the U. S. government. This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. springeronline.com ©
Springer-Verlag Berlin Heidelberg 2004
Originally published by Springer-Verlag Berlin Heidelberg New York In 2004
Softcover reprint of the hardcover 1st edition 2004 The use of general descriptive names, registered names, trademarks, etc. in this publications does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Editor: Ute Heilmann, Heidelberg Desk editor: Dorthe Mennecke-BUhler, Heidelberg Production editor: Bernd Wieland, Heidelberg Cover design: F. Steinen, 'Studio Calamar, Spain Typesetting: AM-productions GmbH, Wiesloch
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Acknowledgments
Positron emission tomography provides unprecedented insights into human brain function in both health and disease, but is a complex endeavor involving many scientific disciplines. It would therefore have been impossible to write this book without the support of many friends and colleagues. We are deeply indebted to them all. Several colleagues made essential contributions to this book. Lutz Kracht and Johannes Klein at the Max Planck Institute in Cologne selected and prepared many of the images used in the figures. W