Positron Emission Tomography

Oncological imaging has thoroughly changed in the past decade, especially due to the introduction of PET and 18FDG. In Positron Emission Tomography, expert referring specialists and professional imagers seek to help bridge some of the knowledge gaps in se

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Malik E. Juweid Otto S. Hoekstra Editors

Positron Emission Tomography

Methods

in

Molecular Biology™

Series Editor John M. Walker School of Life Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK



For other titles published in this series, go to www.springer.com/series/7651

Positron Emission Tomography Edited by

Malik E. Juweid Department of Radiology, University of Iowa, Iowa City, IA, USA

Otto S. Hoekstra Department of Nuclear Medicine & PET Research, VU University Medical Centre, Amsterdam, The Netherlands

Editors Malik E. Juweid, MD Department of Radiology and the Holden Comprehensive Cancer Center, University of Iowa Iowa City, IA, USA [email protected]

Otto S. Hoekstra, MD Department of Nuclear Medicine & PET Research, VU University Medical Centre Amsterdam, The Netherlands [email protected]

ISSN 1064-3745 e-ISSN 1940-6029 ISBN 978-1-61779-061-4 e-ISBN 978-1-61779-062-1 DOI 10.1007/978-1-61779-062-1 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011921313 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or ­dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, ­neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)

Preface Oncological imaging has thoroughly changed in the past decade, especially due to the introduction of PET and 18FDG. For the first time, technology was challenged to provide evidence of (cost-) effectiveness, and this demand has resulted in many excellent trials. Meanwhile, PET-CT was introduced, and this made the PET technology even more appealing for those who were still getting used to the anatomy-deprived PET images. At the same time, oncological patient care evolved toward a truly multidisciplinary effort, combining the expertise of oncologists, surgeons, radiotherapists, radiologists, nuclear medicine physicians, and pathologists. The current challenge is to use common language and develop skills at the boundaries of each other’s area of exp