Nitric Oxide, Oxidant Status and Antioxidant Response in Morbidly Obese Patients: the Impact of 1-Year Surgical Weight L
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CLINICAL RESEARCH
Nitric Oxide, Oxidant Status and Antioxidant Response in Morbidly Obese Patients: the Impact of 1-Year Surgical Weight Loss Adriana Florinela Cătoi & Alina Pârvu & Romeo Florin Galea & Ioana Delia Pop & Adriana Mureşan & Cornel Cătoi
# Springer Science+Business Media New York 2013
Abstract Background The aims of this study were to evaluate nitric oxide (NO) metabolites (nitrite/nitrate NOx) as proinflammatory parameter and total oxidant status (TOS) as well as total antioxidant response (TAR) as oxidative stress (OS) markers in morbidly obese (MO) patients in comparison with normal-weight healthy (NWH) subjects and to determine the post-bariatric surgery changes of NOx and OS indicators in relation with weight loss. Methods We examined serum NOx, TOS, and TAR in a bariatric group of MO patients and a NWH control group (n=23 each group). In the NWH group, serum was examined once, while in the MO group, serum was examined before and at 3, 6, and 12 months after silastic ring vertical gastroplasty (SRVG). Results Serum NOx and TOS values were higher (p
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