ONCOR: design of the Dutch cardio-oncology registry

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Neth Heart J https://doi.org/10.1007/s12471-020-01517-8

ONCOR: design of the Dutch cardio-oncology registry J. A. M. Kamphuis · M. Linschoten · M. J. Cramer · F. Alsemgeest · D. J. W. van Kessel · K. Urgel · M. C. Post · O. C. Manintveld · H. C. Hassing · C. Liesting · A. J. Wardeh · E. G. M. Olde Bijvank · J. Schaap · A. M. Stevenseden Boer · P. A. Doevendans · F. W. Asselbergs · A. J. Teske

Accepted: 20 October 2020 © The Author(s) 2020

Abstract Background The relative new subspecialty ‘cardiooncology’ was established to meet the growing demand for an interdisciplinary approach to the management of cancer therapy–related cardiovascular adverse events. In recent years, specialised cardio-oncology services have been implemented worldwide, which all strive to improve the cardiovascular health of cancer patients. However, limited data are currently available on the outcomes and experiences of these specialised services, and optimal strategies for cardiooncological care have not been established. Aim The ONCOR registry has been created for prospective data collection and evaluation of cardiooncological care in daily practice.

Methods Dutch hospitals using a standardised cardiooncology care pathway are included in this national, multicentre, observational cohort study. All patients visiting these cardio-oncology services are eligible for study inclusion. Data collection at baseline consists of the (planned) cancer treatment and the cardiovascular risk profile, which are used to estimate the cardiotoxic risk. Information regarding invasive and noninvasive tests is collected during the time patients receive cardio-oncological care. Outcome data consist of the incidence of cardiovascular complications and major adverse cardiac events, and the impact of these events on the oncological treatment.

Electronic supplementary material The online version of this article (https://doi.org/10.1007/s12471-020-01517-8) contains supplementary material, which is available to authorized users.

A. J. Wardeh · E. G. M. Olde Bijvank Department of Cardiology, Haaglanden Medical Center, The Hague, The Netherlands

J. A. M. Kamphuis · M. Linschoten · M. J. Cramer · M. C. Post · P. A. Doevendans · F. W. Asselbergs · A. J. Teske () Department of Cardiology, Division of Heart and Lungs, University Medical Centre Utrecht, University of Utrecht, Utrecht, The Netherlands [email protected] F. Alsemgeest Department of Cardiology, St Jansdal Hospital, Harderwijk, The Netherlands D. J. W. van Kessel · K. Urgel · M. C. Post Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands O. C. Manintveld · H. C. Hassing Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands

J. Schaap Department of Cardiology, Amphia Hospital, Breda, The Netherlands A. M. Stevense-den Boer Department of Internal Medicine, Amphia Hospital, Breda, The Netherlands P. A. Doevendans Central Military Hospital, Utrecht, The Netherlands P. A. Doevendans · F. W. Asselbergs Netherlands Heart Institute, Utrecht, The Netherlands F. W. As