Ovarian Cancers Advances through International Research Cooperation
This book provides an overview of the latest developments in the concepts and management of ovarian cancer. The new data presented throughout opens the way to radically different therapeutic approaches. Surgery remains the core of ovarian cancer treatment
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Ovarian Cancers Advances through International Research Cooperation (GINECO, ENGOT, GCIG)
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Ovarian Cancers
Eric Pujade-Lauraine Isabelle Ray-Coquard • Fabrice Lécuru Editors
Ovarian Cancers Advances through International Research Cooperation (GINECO, ENGOT, GCIG)
Editors Eric Pujade-Lauraine AP-HP Hôtel-Dieu Paris France
Fabrice Lécuru Chirurgie cancérologique HEGP Paris France
Isabelle Ray-Coquard Centre Léon Bérard Université Claude Bernard Lyon France
ISBN 978-3-319-32108-0 ISBN 978-3-319-32110-3 DOI 10.1007/978-3-319-32110-3
(eBook)
Library of Congress Control Number: 2016953670 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
Preface
Ovarian cancer is the leading cause of death from gynecological cancers in western countries. A huge effort in clinical research has been conducted during the last 20 years thanks to a unique organization of national networks dedicated to gynecology oncology. National networks, such as GINECO (Groupe des Investigateurs Nationaux pour l’Etude des Cancers de l’Ovaire et du sein) in France, have grouped together and joined forces at the European level through the ENGOT (European Network of Gynecology Oncology Trials). This European network has been integrated at a global level within GCIG (Gynecologic Cancer InterGroup) with twice a year meetings, offering to Europe, America, Asia, and Australia a platform for scientific exchange and debates. Treatment of advanced ovarian cancer (FIGO stages III and IV) until recently consisted of cytoreductive surgery and paclitaxel/carboplatin chemotherapy. However, a great debate has risen when two consecutive trials have suggested that three cycles of neoadjuvant chemotherapy could decrease the toxicity of extensive debulking surgery. In this debate presented by F Lecuru, the most imp
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