Oxygen availability affects exercise capacity, but not neuromuscular fatigue characteristics of knee extensors, during e

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ORIGINAL ARTICLE

Oxygen availability affects exercise capacity, but not neuromuscular fatigue characteristics of knee extensors, during exhaustive intermittent cycling Olivier Girard1,2   · Martin Buchheit3,4 · Stuart Goodall5   · Sébastien Racinais2  Received: 16 July 2020 / Accepted: 5 September 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Purpose  To compare the effects of different hypoxia severities on exercise capacity, cardio-respiratory, tissue oxygenation and neuromuscular fatigue characteristics in response to exhaustive intermittent cycling. Methods  Eleven well-trained cyclists, repeated supra-maximal cycling efforts of 15 s (30% of anaerobic power reserve, 609 ± 23 W), interspersed with 45 s of passive rest until task failure. The exercise was performed on separate days in normoxia (SL; simulated altitude/end-exercise arterial oxygen saturation = 0 m/~ 96%), moderate (MH; 2200 m/~ 90%) and severe (SH; 4200 m/~ 79%) hypoxia in a cross-over design. Neuromuscular tests, including brief (5 s) and sustained (30 s) maximal isometric voluntary contractions of the knee extensors, were performed at baseline and exhaustion. Results  Exercise capacity decreased with hypoxia severity (23 ± 9, 16 ± 6 and 9 ± 3 cycle efforts in SL, MH and SH, respectively; P