Oxymetazoline overdose
- PDF / 151,875 Bytes
- 1 Pages / 595.245 x 841.846 pts (A4) Page_size
- 56 Downloads / 140 Views
1 OS
Oxymetazoline overdose Respiratory arrest and coma secondary to drug used in unapproved age group: case report
A 21-day-old boy developed respiratory arrest and coma during following overdose of oxymetazoline for cold and cough. Also, treatment with oxymetazoline was administered in unapproved age group leading to medication error. The boy presented to a hospital in India with decreased activity, refusal of feeds, an episode of a staring look, shrill cry and respiratory distress. He was born by cesarean section in view of pregnancy induced hypertension with a birth weight of 3.2 kg. He cried immediately after birth and was exclusively breastfed. On day 19 of life, he developed cold and cough and was prescribed medicines in an outpatient department. Two days later, he was admitted to hospital with decreased activity, shrill cry, refusal of feeds and an episode of a staring look for a few seconds. On admission, he was lethargic, euglycemic and had a respiratory distress with room air saturation of 70%. His peripheries were cold with prolonged capillary refill time, and systemic examination was unremarkable. He was initiated on supplemental oxygen through nasal prongs and a normal saline bolus. His conditioned worsened with shallow breathing progressing to apnea required mask and bag ventilation. Endotracheal intubation was performed after he developed respiratory arrest. He was transferred to the NICU on bag and endotracheal tube, and ventilation was initiated on ventilatory support. The boy was initiated on cefotaxime and treatment continued for 48 hours. His other laboratory parameters were found to be normal. Initially, orogastric tube feeds were initiated after 4 hours of admission, and later, oral feeds were introduced on day 4. He was discharged on day 6 with normal health condition. No recurrence was noted on regular follow-up. On anamnesis, it was revealed that he was prescribed with oxymetazoline 0.01% nasal decongestant drops by a local pediatrician prior to current hospitalisation. Based on the findings, a diagnosis of oxymetazoline-induced coma secondary to oxymetazoline administration in unapproved age group was considered. Also, possibility of overdose could not be excluded due to retrospectively recorded dosage and unavailability to measure the plasma imidazoline levels. Suraneni S, et al. Oxymetazoline-induced respiratory arrest due to nasal decongestants. Perinatology 20: 25-27, No. 1, Apr-Jun 2019. Available from: URL: https:// www.perinatology.in/s/Oxymetazoline-Induced-Respiratory-Arrest.pdf
0114-9954/20/1834-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved
803520234
Reactions 12 Dec 2020 No. 1834
Data Loading...
