Pathology and Epidemiology of Cancer
Pathology and Epidemiology of Cancer integrates the disciplines of Cancer Pathology and Epidemiology to provide a synergistic and complementary approach to understanding the molecular mechanisms of cancer. This book provides relevant information on the di
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Pathology and Epidemiology of Cancer
Massimo Loda Lorelei A. Mucci Megan L. Mittelstadt Mieke Van Hemelrijck Maura Bríd Cotter •
Editors
Pathology and Epidemiology of Cancer
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Editors Massimo Loda Department of Pathology Dana-Farber Cancer Institute and Brigham & Women’s Hospital, Harvard Medical School Boston, MA USA Lorelei A. Mucci Department of Epidemiology Harvard T.H. Chan School of Public Health Boston, MA USA
Mieke Van Hemelrijck Guy’s Hospital King’s College London London UK Maura Bríd Cotter Department of Pathology Dana-Farber Cancer Institute and Brigham & Women’s Hospital, Harvard Medical School Boston, MA USA
Megan L. Mittelstadt Department of Genetics Harvard Medical School Boston, MA USA
ISBN 978-3-319-35151-3 DOI 10.1007/978-3-319-35153-7
ISBN 978-3-319-35153-7
(eBook)
Library of Congress Control Number: 2016940001 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
Preface
The conception of this book arose from an ongoing course created in 2010 for Cancer Biology Ph.D. students at Harvard Medical School, entitled “The Epidemiology and Molecular Pathology of Cancer.” A series of general lectures begins the course, upon which the introductory chapters of this text are based. Each subsequent day of the course is dedicated to a single cancer type, with lecturers providing an overview of the cancer from the points-of-view of both an epidemiologist and a pathologist. The course, and thus this text, is unique in that it integrates the disciplines of cancer pathology and epidemiology, ranging from population-based understandings to detailed molecular mechanisms to provide a synergistic and comprehensive view of cancer pathogenesis. Pathology is at the cornerstone of cancer pathogenesis, diagnosis, prognosis, and treatment. While other books may
