Pattern Recognition in Bioinformatics 7th IAPR International Con

This book constitutes the refereed proceedings of the 7th International Conference on Pattern Recognition in Bioinformatics, PRIB 2012, held in Tokyo, Japan, in November 2012. The 24 revised full papers presented were carefully reviewed and selected from

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Edited by S. Istrail, P. Pevzner, and M. Waterman Editorial Board: A. Apostolico S. Brunak M. Gelfand T. Lengauer S. Miyano G. Myers M.-F. Sagot D. Sankoff R. Shamir T. Speed M. Vingron W. Wong

Subseries of Lecture Notes in Computer Science

Tetsuo Shibuya Hisashi Kashima Jun Sese Shandar Ahmad (Eds.)

Pattern Recognition in Bioinformatics 7th IAPR International Conference, PRIB 2012 Tokyo, Japan, November 8-10, 2012 Proceedings

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Series Editors Sorin Istrail, Brown University, Providence, RI, USA Pavel Pevzner, University of California, San Diego, CA, USA Michael Waterman, University of Southern California, Los Angeles, CA, USA Volume Editors Tetsuo Shibuya The University of Tokyo, Institute of Medical Science 4-6-1 Shirokanedai, Minato-ku, 108-8639 Tokyo, Japan E-mail: [email protected] Hisashi Kashima The University of Tokyo, Department of Mathematical Informatics 7-3-1 Hongo, Bunkyo-ku, 113-8654 Tokyo, Japan E-mail: [email protected] Jun Sese Tokyo Institute of Technology, Department of Computer Science 2-12-1 Ookayamama, Meguro-ku, 152-8550 Tokyo, Japan E-mail: [email protected] Shandar Ahmad National Institute of Biomedical Innovation 7-6-8 Saito-Asagi, Suita, 567-0085 Osaka, Japan E-mail: [email protected]

ISSN 0302-9743 e-ISSN 1611-3349 ISBN 978-3-642-34122-9 e-ISBN 978-3-642-34123-6 DOI 10.1007/978-3-642-34123-6 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2012948870 CR Subject Classification (1998): J.3, I.5, F.2.2, I.2, I.4, H.3.3, H.2.8 LNCS Sublibrary: SL 8 – Bioinformatics © Springer-Verlag Berlin Heidelberg 2012 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Typesetting: Camera-ready by author, data conversion by Scientific Publishing Services, Chennai, India Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface

The Pattern Recognition in Bioinformatics (PRIB) meeting was established in 2006 under the auspices of the International Association for Pattern Recognition (IAPR) to create a focus for the development and application of pattern recognition techniques in the biological domain. Since its establishment, PRIB has brought together top researchers, practitioners, and students from aroun