Perinatal Stem Cells Biology, Manufacturing and Translational Medici

This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury. Currently, the limitations of pos

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Perinatal Stem Cells

Zhong Chao Han Tsuneo A. Takahashi Zhibo Han  •  Zongjin Li Editors

Perinatal Stem Cells Biology, Manufacturing and Translational Medicine

Editors Zhong Chao Han Beijing Engineering Laboratory of Perinatal Stem Cells Jiangxi Engineering Research Center for Stem Cell, Health & Biotech Co. Beijing

China Zhibo Han State Key Lab of Experimental Hematology Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical Sciences Tianjin China

Tsuneo A. Takahashi Institute for Frontier Medical Sciences Kyoto University Kyoto Japan Zongjin Li School of Medicine Nankai University Tianjin China

ISBN 978-981-13-2702-5    ISBN 978-981-13-2703-2 (eBook) https://doi.org/10.1007/978-981-13-2703-2 Library of Congress Control Number: 2019930130 © Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Contents

1 Introduction of Perinatal Tissue-­Derived Stem Cells ������������������   1 Zongjin Li and Zhong Chao Han 2 The Regenerative and Reparative Potential of Amniotic Membrane Stem Cells����������������������������������������������������������������������   9 Mirja Krause, Jonathan Lozano, and Rebecca Lim 3 The Stemness of Perinatal Stem Cells��������������������������������������������  27 Yan Zhang, Zongjin Li, and Na Liu 4 Quality Assessment of Umbilical Cord Tissue in Newborn Stem Cell Banking ������������������������������������������������������������������������������������  39 Katherine Stewart Brown 5 Safety and Genetic Stability of Cultured Perinatal Mesenchymal Stem Cells ����������������������������������������������������������������������������������������  47 Youwei W