Physical Exercise and Quality of Life of Patients Diagnosed with Colorectal Cancer: Systematic Literature Review

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Physical Exercise and Quality of Life of Patients Diagnosed with Colorectal Cancer: Systematic Literature Review Kleber Henrique da Silva Bezerra 1 & Marcelo Vaughan Lima de Oliveira 1 & Israel Junior Borges do Nascimento 2 Letícia de Barros Rocha 3 & Luiz Euclides Coelho de Souza Filho 4 & Rodrigo Santiago Barbosa Rocha 3 & Marianne Lucena da Silva 2 & Katiane da Costa Cunha 1

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# Springer Science+Business Media, LLC, part of Springer Nature 2020

Abstract Background Colorectal cancer decrease quality of life, due to treatment and disease, and physical exercise can improve the quality of life of patients with cancer, but it is still uncertain whether physical exercise can improve quality of life in these patients. Aim To determine if there is an improvement in the quality of life in patients diagnosed with colorectal cancer undergoing physical exercise. Methods A systematic literature review was carried out; non-randomized clinical trials of any year were included from PubMed, Embase, Cochrane, and VHL platforms, without specific language delimitation, and analyzed the influence of physical exercise on the quality of life of patients diagnosed with colorectal cancer, and for analysis of bias, the Cochrane Manual for the Development of Systematic Intervention Reviews was used. Results Four studies were analyzed in full to produce the results; of these, three intervened with unsupervised aerobic exercises and one with semi-supervised aerobic exercises, all used the FACT-C as a questionnaire to assess quality of life, some even used FACT-G and/or SF-12, and only one author found significance values in the variables of physical well-being, emotional wellbeing, and functional well-being of the questionnaire, compared with the control group. Conclusion There were no significant increases in the quality of life of patients diagnosed with colorectal cancer compared with the control group. Keywords Colon cancer . Colorectal cancer . Exercise . Rectal neoplasia . Quality of life

Introduction Cancer is one of the main causes of death in the world, accounting for approximately 12% of death cases annually, bringing a series of systemic repercussions [1–3]. In this Electronic supplementary material The online version of this article (https://doi.org/10.1007/s12029-020-00506-9) contains supplementary material, which is available to authorized users. * Rodrigo Santiago Barbosa Rocha [email protected] 1

State University of Pará, Marabá, Pará, Brazil

2

Federal University of Jataí, Jataí, Brazil

3

State University of Pará, Belém, Pará, Brazil

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Ophir Loyola Hospital, Belém, Pará, Brazil

sense, it is important to know about colorectal cancer, the third most diagnosed in men and the second in women. Such malignant neoplasms correspond both to the colon (104,610 new cases per year in the USA) and to the rectum (43,340 new cases per year in the USA). In 2018, 1.8 million new cases of the disease were diagnosed and 861,000 deaths [4]. Although treatment improves patient survival, the literature poi