Pituitary Disorders of Childhood Diagnosis and Clinical Management

This unique book presents an up-to-date discussion of clinical disorders of the pituitary gland in children with specific emphasis on state-of-the-art diagnostic and treatment modalities, highlighting the newest scientific advances in genomics and molecul

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Brenda Kohn Editor

Pituitary Disorders of Childhood Diagnosis and Clinical Management

Contemporary Endocrinology Series Editor Leonid Poretsky Division of Endocrinology Lenox Hill Hospital New York, NY, USA

More information about this series at http://www.springer.com/series/7680

Brenda Kohn Editor

Pituitary Disorders of Childhood Diagnosis and Clinical Management

Editor Brenda Kohn Division of Pediatric Endocrinology New York University New York, NY USA

ISSN 2523-3785     ISSN 2523-3793 (electronic) Contemporary Endocrinology ISBN 978-3-030-11338-4    ISBN 978-3-030-11339-1 (eBook) https://doi.org/10.1007/978-3-030-11339-1 Library of Congress Control Number: 2019935846 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Humana Press imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Series Editor Foreword

Because of its crucial role in regulating multiple endocrine functions, the pituitary gland is known in endocrine parlance as the “master gland.” Normal pituitary function is particularly important in childhood—a period of rapid growth and development. The subject of pituitary disorders of childhood, therefore, is an extremely important topic for physicians who provide medical care for the children and families affected by these conditions. This volume, edited by Dr. Brenda Kohn, is an encyclopedic compilation of recent scientific research and clinical guidelines that are essential for the recognition and care of children with congenital and acquired disorders of the pituitary gland. It addresses embryology and genetics, pituitary tumors and non-pituitary tumors that may affect pituitary function, hypothalamic/pituitary functional deficiencies, the effects of childhood cancer treatment and of traumatic b