Plasma Cell Neoplasms Pathogenesis, Diagnosis and Laboratory Evaluat
This book provides an overview of our current understanding of the pathogenesis of the plasma cell neoplasms and comprehensively updates the reader on the laboratory techniques used in the diagnosis and prognostication of these malignancies as well as for
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Plasma Cell Neoplasms
Robert B. Lorsbach Marwan Yared •
Editors
Plasma Cell Neoplasms Pathogenesis, Diagnosis and Laboratory Evaluation
123
Editors Robert B. Lorsbach Department of Pathology and Laboratory Medicine Cincinnati Children’s Hospital Medical Center, University of Cincinnati College of Medicine Cincinnati, OH USA
ISBN 978-3-319-42368-5 DOI 10.1007/978-3-319-42370-8
Marwan Yared Department of Pathology and Immunology Baylor College of Medicine Houston, TX USA
ISBN 978-3-319-42370-8
(eBook)
Library of Congress Control Number: 2016945872 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
Contents
1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Marwan Yared and Robert B. Lorsbach
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2 Clinical Features, Management, and Therapy of Plasma Cell Neoplasms: What Pathologists Need to Know . . . . . . . . . . . . . . . . . Giampaolo Talamo, Cerisse Harcourt and Maurizio Zangari
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3 Morphologic and Immunohistochemical Evaluation of Plasma Cell Neoplasms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Soumya Pandey and Robert B. Lorsbach
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4 Cytogenetics of Plasma Cell Neoplasms. . . . . . . . . . . . . . . . . . . . . . Jeffrey R. Sawyer 5 Flow Cytometric Analysis in the Diagnosis and Prognostication of Plasma Cell Neoplasms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Pei Lin
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6 Renal Manifestations of Plasma Cell Neoplasms . . . . . . . . . . . . . . . 109 L. Nicholas Cossey and Shree G. Sharma Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153
v
Contributors
Cerisse Harcourt Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR
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