Plasma
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Plasma Transfusion-related acute lung injury: case report
A 7-year-old girl developed transfusion-related acute lung injury following treatment with plasma for haemolytic uraemic syndrome (HUS). The girl was diagnosed with HUS and plasmapheresis and haemodialysis were planned. After hemodialysis, plasmapheresis was performed with 4 units of fresh frozen plasma [route not stated]. During plasmapheresis, there was no problem. However, after 1 hour, she developed tachypnea, respiratory distress, desaturation and tachycardia. The girl received oxygen support. Physical examination showed equal respiratory sounds in both hemi thorax, but diminished bilaterally. Rales-rhonchus was not detected and heart beats were rhythmic. There were no murmur or other additional sounds and no oedema-acid or hepatomegaly. Posteroanterior (PA) chest X-ray showed bilateral diffuse irregular reticulonodular infiltrates. Sudden respiratory failure following plasmapheresis was attributed to transfusion-related acute lung injury. She was treated with methylprednisolone. During follow-up, her respiratory distress regressed and oxygen necessity decreased. Mechanical ventilation was also not required. PA chest X-ray showed regressed infiltrations. Monitoring with haemodialysis continued. Her respiratory distress regressed. Plasmapheresis was not repeated again. Polat AC, et al. Transfusion-related acute lung injury: A case report. Journal of Pediatric Research 7: 365-3367, No. 4, Jan 2020. Available from: URL: http:// www.jpedres.org/search-result?search=Transfusion-related%20acute%20lung%20injur
0114-9954/20/1823-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved
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Reactions 26 Sep 2020 No. 1823
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