Platelet indices as a predictive marker in neonatal sepsis and respiratory distress in preterm prelabor rupture of membr
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ORIGINAL ARTICLE
Platelet indices as a predictive marker in neonatal sepsis and respiratory distress in preterm prelabor rupture of membranes Sanjay Mishra1 · Shyampyari Jaiswar2 · Sumaiya Saad2 · Shalini Tripathi3 · Nisha Singh2 · Sujata Deo2 · Monika Agarwal2 · Neetu Mishra1 Received: 3 June 2020 / Revised: 25 September 2020 / Accepted: 5 October 2020 © Japanese Society of Hematology 2020
Abstract Preterm Prelabor rupture of membranes (PPROM) accompanies 2–3% of all pregnancies and 1/3rd of all preterm deliveries leading to intraamniotic infection, postpartum infections, sepsis along with perinatal morbidity and mortality worldwide. Early diagnosis and treatment can prevent the complications of PPROM and improve mother and child health. The platelet indices (platelet count, Mean platelet volume, Plateletcrit and Immature platelet fraction) could be a useful predictive parameters in PPROM, as platelets are acute phase reactants and there parameters may vary with inflammation and increased platelet consumption/production. In the present study, Mean Platelet volume (MPV) levels showed significant increase in cases as compared to controls (10.47 ± 1.92 fl Vs 8.84 ± 1.30 fl; P
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