Practical Manual of In Vitro Fertilization Advanced Methods and Nove

The Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is a unique, accessible title that provides a complete review of the most well-established and current diagnostic and treatment techniques comprising in vitro fertilization

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Zsolt Peter Nagy • Alex C. Varghese Ashok Agarwal Editors

Practical Manual of In Vitro Fertilization Advanced Methods and Novel Devices

Editors Zsolt Peter Nagy, MD, PhD, HCLD (ABB), EMB (ACE) Scientific and Laboratory Director Reproductive Biology Associates Atlanta, GA 30342, USA

Alex C. Varghese, PhD Senior Embryologist Montreal Reproductive Centre Montreal, QC H4A 3J3, Canada

Ashok Agarwal, PhD, HCLD (ABB), EMB (ACE) Director, Center for Reproductive Medicine Cleveland Clinic, Euclid Avenue 9500 Cleveland, OH 44195, USA

ISBN 978-1-4419-1779-9 e-ISBN 978-1-4419-1780-5 DOI 10.1007/978-1-4419-1780-5 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2012934564 © Springer Science+Business Media, LLC 2012 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Foreword

Even more than 3 decades after the birth of Louise Brown and the birth of several millions of children conceived by numerous procedures of assisted reproductive technology (ART), the Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is very welcome. The book is edited by Zsolt Peter Nagy, Alex Varghese, and Ashok Agarwal and consists of more than 70 different chapters written by experts in the field. The authors are mostly from North America, but the book includes some experts from Europe and Australia. The large numbers of chapters are categorized into different major sections: general organization of ART laboratory, the equipment and culture systems used, the characteristics of the oocytes, different procedures of embryo culture, sperm processing and selection, different insemination procedures, the evaluation and grading of embryos, biopsy of oocytes and embryos, cryopreservation of gametes, embryos and tissues, embryo transfer procedures, accreditation and licensing and legislation in different countries. The last part of the Manual consists of a series of special topics. As is the