Practice and Progress in Cardiac Pacing and Electrophysiology
Developments in the electrical treatment of arrhythmias have been so fast over the last few years that access to available, state-of-the-art knowledge has become a major challenge. The proceedings of scientific meetings are therefore most helpful in this
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PRACTICE AND PROGRESS IN CARDIAC PACING AND ELECTROPHYSIOLOGY edited by
M.ALIOTO Department of Cardiology, Hacettepe University, School of Medicine, Ankara, Turkey
KLUWER ACADEMIC PUBLISHERS DORDRECHT / BOSTON / LONDON
Library of Congress Cataloging-in-Publication Data Practice and progress in cardiac pacing and electrophysiology I edited by Ali M. Oto. p. cm. -- (Developments in cardiovascular medicine; v. 183) Includes index. ISBN-l 3: 978-94-010-6582-5 e-ISBN-l 3: 978-94-009-0219-0 001: 10.1007/978-94-009-0219-0 1. Cardiac pacing. 2. Arrhythmia--Treatment. 3. Implantable cardioverter-deflbri llators. 4. Heart--Electric properties. 1. Oto, Ali. II. Series. [ONLM: 1. Cardiac Pacing, Artificial. 2. Arrhythmia--therapy. 3. Pacemaker, Artificial. 4. Electrophysiology. WI DE997VME v.183 1996 / WG 168 P8954 1996] RC684.P3P755 1996 617.4' 120645--dc20 ONLM/OLC 96-116 for Library of Congress
ISBN·13:978-94-0l0-6S82-S Published by Kluwer Academic Publishers, P.O. Box 17,3300 AA Dordrecht, The Netherlands. Kluwer Academic Publishers incorporates the publishing programmes of D. Reidel, Martinus Nijhoff, Dr W. Junk and MTP Press. Sold and distributed in the U.S.A. and Canada by Kluwer Academic Publishers, 101 Philip Drive, Norwell, MA 02061, U.S.A. In all other countries, sold and distributed by Kluwer Academic Publishers Group, P.O. Box 322, 3300 AH Dordrecht, The Netherlands.
Printed on acid-free paper
All Rights Reserved © 1996 Kluwer Academic Publishers Softcover reprint of the hardcover 1st edition 1996 No part of the material protected by this copyright notice may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording or by any information storage and retrieval system, without written permission from the copyright owner.
To the memory of my father, Nuri Oto, M.D.
Contents
Foreword
xiii xv
Preface List of Contributors
xvii
PART ONE: ARRHYTHMIAS AND ANTIARRHYTHMIC TREATMENT STRATEGIES l. Endpoints and trials: a matter of life and death. Classification
of death in patients under antiarrhythmic treatment Hugo Ector
2. The role of transient ischaemia in the pathophysiology of ventricular arrhythmias in patients with coronary artery disease Sergio L. Chierchia, Alberto Margonato & Alessandra Mailhac
7
3. Sudden death and tachyarrhythmias in athletes Luc lordaens
13
4. The evaluation of antiarrhythmics Philippe Coumel
23
5. Atrial fibrillation: maintaining the sinus rhythm
29
Samuel Levy
6. Arrhythmogenic right ventricular dysplasia Paolo Rizzon, Maria Vittoria Pitzalis, Giovanni Luzzi, Francesco Massari & Filippo Mastropasqua vii
37
Vlll
Contents
PART TWO: NON-INVASIVE ELECTROCARDIOLOGY 7. Signal averaged electrocardiogram. Current applications and limitations Thomas S. Faber & Marek Malik
47
8. Can analysis of heart rate variability predict arrhythmias and antiarrhythmic effects? Ronald W.E Campbell
63
9. QT dispersion Ronald W.E Campbell
71
10. Use of baroreceptor reflex sensitivity in the prediction of risk after myocardial