Pre-radiosurgery leucocyte ratios and modified glasgow prognostic score predict survival in non-small cell lung cancer b
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CLINICAL STUDY
Pre‑radiosurgery leucocyte ratios and modified glasgow prognostic score predict survival in non‑small cell lung cancer brain metastases patients Anna Cho1 · Helena Untersteiner1 · Dorian Hirschmann1 · Fabian Fitschek1 · Christian Dorfer1 · Karl Rössler1 · Sabine Zöchbauer‑Müller2 · Brigitte Gatterbauer1 · Maximilian J. Hochmair3 · Josa M. Frischer1 Received: 18 September 2020 / Accepted: 5 November 2020 © The Author(s) 2020
Abstract Introduction The predictive value of the pre-radiosurgery Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), Lymphocyte-to-Monocyte Ratio (LMR) and the modified Glasgow Prognostic Score (mGPS) was assessed for the first time in a homogenous group of NSCLC brain metastaes (BM) patients. Methods We retrospectively evaluated 185 NSCLC-BM patients, who were treated with Gamma Knife Radiosurgery (GKRS). Patients with immunotherapy or targeted therapy were excluded. Routine laboratory parameters were reviewed within 14 days before GKRS1. Results Median survival after GKRS1 was significantly longer in patients with NLR
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