Primary cardiac dedifferentiated liposarcoma in a middle-aged female: a case report
- PDF / 1,282,473 Bytes
- 6 Pages / 595.276 x 790.866 pts Page_size
- 70 Downloads / 208 Views
(2019) 14:156
CASE REPORT
Open Access
Primary cardiac dedifferentiated liposarcoma in a middle-aged female: a case report Jiayu Shen1†, Zhi Fang1†, Yahan Zhang2† and Yingqiang Guo1*
Abstract Background: Primary malignant cardiac tumors are extremely rare and can present with the same nonspecific characteristics as benign primary cardiac tumors. We herein describe a middle-aged female with an intracavitary, irregular atrial mass who experienced partial surgical resection. The atrial mass which was recognized as myxoma before surgery was finally diagnosed as dedifferentiated liposarcoma (DDLPS) by postoperative pathological examination. Case presentation: The patient, a 61-year-old female, presented to the emergency room because of progressive chest congestion and shortage of liberties for 6 months and orthopnoea and paroxysmal nocturnal dyspnea for 3 days. The laboratory examinations confirmed no abnormalities. The thoracic computed tomography (CT) scan showed massive hydropericardium, pleural effusion and left atrium occupying lesion. The transesophageal echocardiography (TEE) confirmed an intracavitary and irregular left atrial mass, limiting the mitral valve inflow and pulmonary venous blood reflux. The positron emission tomography/computed tomography (PET/CT) revealed high grade fluorodeoxyglucose uptake only in the intracavitary mass which near the mitral valve. According to operative exploration, the intracavitary mass had invaded the mitral annulus and posterior wall of left ventricle which cannot be resected completely, we did merely partial surgical resection to relieve the patient’s symptoms. Postoperative immunohistochemical stain confirmed the diagnosis of DDLPS. The patient was transferred to the oncology department for further therapy. Unfortunately, the patient was detected with brain metastasis 1 month later and died within 5 months after the surgery. Conclusions: Primary cardiac DDLPS is an extremely rare histological subtype of undifferentiated pleomorphic sarcomas which present the same nonspecific characteristics as benign primary cardiac tumors. Even though surgical resection combined with chemotherapy or radiotherapy remains the mainstream treatment strategy, the prognosis of cardiac malignancy is poor with high mortality. Novel management strategies need to be further explored. Keywords: Dedifferentiated liposarcoma, Heart failure, Intracavitary atrial mass, Pleural effusion, Primary malignant cardiac tumor
* Correspondence: [email protected] † Jiayu Shen, Zhi Fang and Yahan Zhang contributed equally to this work. 1 Department of Cardiovascular Surgery, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, Sichuan, People’s Republic of China61004 Full list of author information is available at the end of the article © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medi
Data Loading...
