Principles and Practice of Cancer Infectious Diseases
Principles and Practice of Cancer Infectious Diseases is a comprehensive and insightful work dedicated to elucidating the problem of infections in cancer patients. This essential volume reviews common and less often encountered infections, while esta
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Current Clinical Oncology Maurie Markman, MD, Series Editor
For other titles published in this series, go to www.springer.com/series/7631
Amar Safdar Editor
Principles and Practice of Cancer Infectious Diseases
Editor Amar Safdar Department of Infectious Diseases, Infection Control, and Employee Health The University of Texas M.D. Anderson Cancer Center Houston, TX USA [email protected]
ISBN 978-1-60761-643-6 e-ISBN 978-1-60761-644-3 DOI 10.1007/978-1-60761-644-3 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011928679 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)
This book is dedicated for promoting excellence in care and well-being for the patients with cancer.
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Preface
Patients with cancer are highly susceptible to infections. These infections are inclined to be difficult to prevent, diagnose, and treat. There are a variety of reasons for this which will be discussed in detail in the chapters of this book. The intent for this book is to provide a comprehensive review of the ever changing spectrum of the management of infectious diseases in this complex population of patients. The changes in patient demography, near-constant global migration of contagious infections, emerging resistance to standard antimicrobial therapy, and the impact of expanding repertoire of antineoplastic therapies including the anticancer biologics and stem cell transplantation have influenced these changes. This book will provide a detailed guide for assessment of risk factors for various infections, evaluating prognosis among susceptible oncology patients with complex issues related to management of opportunistic infections. Strategies to promote hosts’ immune response underscore the future measures based on perspicacious insight in the disease pathogenesis; interaction between the pathogen and
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