Prognostic value of DCTA scoring system in heart failure
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Heart failure (HF) is a global public health problem affecting an estimated 26 million people worldwide [1]. The postdischarge mortality and readmission rates in patients with HF have been unacceptably high: 30–45% of patients with HF are rehospitalized within 1 year and approximately 20% of patients die within 1 year [2, 3]. Although advances in the treatment of HF have resulted in improved prognosis, these data suggest treatment strategies and management remain to be optimized. Evaluating prognostic factors in HF patients has emerged as an important area of research, as it facilitates individualized treatments and an improvement in the prognosis of these patients [4–6]. A range of factors have been reported to have prognostic value in HF. Highsensitivity cardiac troponin T (hs-cTnT) is a strong and independent predictor of all-cause and cardiovascular mortality as well as of hospitalization for cardiovascular causes, and the troponin assay is recommended as a complementary tool Tian-Jun Zhao and Qian-Kun Yang contributed equally to this work and shared the co-authorship. Author contributions Tian-JunZhaoandQian-KunYangperformedthe experiment and wrote the manuscript. Tian-Jun Zhao was responsible for the design of the experiment. Li-Dan Bi and Chun-Yu Tan analyzed the data. Jie Li helped with the statistical analysis. Zhi-Lin Miao provided professional support and revised the manuscript. All authors read and approved the final manuscript. Availability of data and materials The datasets used and/or analyzed during the present study are available from the corresponding author on reasonable request.
Tian-Jun Zhao1 · Qian-Kun Yang2 · Li-Dan Bi1 · Jie Li1 · Chun-Yu Tan1 · Zhi-Lin Miao1 1
Department of Cardiology, The People’s Hospital of China Medical University, The People’s Hospital of Liaoning Province, Shenyang, China 2 Department of Bone and Soft Tissue Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, China
Prognostic value of DCTA scoring system in heart failure for risk stratification [7]. Previously, significant attention was paid to the association between HF and inflammatory indicators, including the neutrophil-tolymphocyte ratio (NLR) or lymphocyteto-monocyte ratio (LMR), which were deemed to be independent predictors of in-hospital and long-term mortality in HF patients [8–10]. In addition, it is generally acknowledged that HF is associated with a prothrombotic state and disturbed blood coagulation system (hemostatic abnormalities; [11]). Among the related factors in this context, D-dimer has been widely studied and is regarded as an important prognostic factor associated with adverse outcome in HF [12–15]. Furthermore, there is abundant evidence in support of the crucial role that nutritional status plays in the prognosis of HF [5, 6, 16]. In particular, serum albumin and total cholesterol level have been shown to be independently correlated with prognosis in HF [17–22]. Recently, the Prognostic Nutritional Index (PNI) and the Controlling Nutritional Statu
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