Propofol
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Hypoxaemia: case report In this single-center, retrospective observational study of 482 patients, who underwent endoscopic retrograde cholangiopancreatography (ERCP) at Medical Center in Japan, between January 2014 and October 2016, an elderly patient [sex and exact age not stated] was described, who developed hypoxaemia during treatment with propofol for sedation. The patient planned to undergo endoscopic retrograde cholangiopancreatography. For this, initially, the patient received local pharyngeal anaesthesia with lidocaine, and pentazocine as an analgesic agent. The sedation was induced with IV propofol infusion 0.6 µg/mL using a diprifusor system, which is a target-controlled infusion (TCI) system incorporating pharmacokinetic parameters. Dose was administered based on target propofol blood concentration. Subsequently, the patient developed hypoxaemia [duration of treatment to reaction onset not stated]. The patient was treated by increasing the per-nasal oxygen dose. Within 30 seconds, the patient recovered from hypoxaemia. Endotracheal intubation was not required. Ogawa T, et al. Propofol sedation with a target-controlled infusion pump in elderly patients undergoing ERCP. Gastrointestinal Endoscopy 92: 301-307, No. 2, Aug 2020. 803499706 Available from: URL: http://doi.org/10.1016/j.gie.2020.03.002
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Reactions 5 Sep 2020 No. 1820
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