Proteases and Their Receptors in Inflammation
Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest. In inflamed tissues, p
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Nathalie Vergnolle
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Michel Chignard
Editors
Proteases and Their Receptors in Inflammation
Editors Nathalie Vergnolle INSERM U 1043 CHU Purpan BP 3028 31024 Toulouse Cedex France [email protected] Series Editors Prof. Michael J. Parnham, Ph.D. Visiting Scientist Research & Clinical Immunology Unit University Hospital for Infectious Diseases “Dr. Fran Mihaljevic´” Mirogojska 8 HR-10000 Zagreb, Croatia
Michel Chignard INSERM U 874 Institut Pasteur Unite de Defense Innee et Inflammation Rue du Dr. Roux 25 75724 Paris Cedex 15 France [email protected] Prof. Eugen Faist, MD, FACS Ludwig-Maximilians-University Munich Klinikum Grosshadern Department of Surgery Marchioninistr. 15 81377 Munich Germany
ISBN 978-3-0348-0156-0 e-ISBN 978-3-0348-0157-7 DOI 10.1007/978-3-0348-0157-7 Library of Congress Control Number: 2011934026 # Springer Basel AG 2011 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. For any kind of use, permission of the copyright owner must be obtained. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Printed on acid-free paper Springer Basel AG is part of Springer Science þ Business Media (www.springer.com)
Preface
For some time, we had in mind to write together on the role of proteases and antiproteases in inflammation. We had considered different options over the years, but concretization was still a long way from our busy schedules. The idea of this book arose in 2009, at the nineth World Congress on Inflammation in Tokyo. We met there at the booth held by Springer Verlag (at that time Birkhenhouse Verlag) with Pr. Vincent Lagente, who had just published in the same series and was presenting his most recent volume. The enthusiasm of Pr. Lagente and the persuasiveness of the publisher representative convinced us that a book on Proteases and their Receptors in Inflammation was the best way to shed some light on the crucial role the protease-anti-protease balance appears to play in inflammatory diseases. We thus embarked on this project, associating colleagues and friends to contribute to the 13 chapters of this book. Each contributor has been a key scientific player in raising new knowledge on the role of proteases, and we want to express here our most sincere gratefulness for the time and energy they spend on their chapters, providing th
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