Psychological aspects of atrial fibrillation: A systematic narrative review
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PSYCHOLOGICAL ASPECTS OF CARDIOVASCULAR DISEASES (A STEPTOE, SECTION EDITOR)
Psychological aspects of atrial fibrillation: A systematic narrative review Impact on incidence, cognition, prognosis, and symptom perception Karl-Heinz Ladwig 1,2,3
&
Andreas Goette 4,5 & Seryan Atasoy 1,3,6 & Hamimatunnisa Johar 2,6
# The Author(s) 2020
Abstract Purpose of the review Atrial fibrillation (AF) is the most frequent arrhythmia in the general population. This review aims to provide a comprehensive overview of the psychological aspects of AF, compiling evidence from epidemiological, clinical, and basic research sources. Recent findings Findings from large-scale population-based and clinical longitudinal studies reveal an association between negative affectivity (e.g. depression) and the incidence and clinical prognosis of AF. Studies investigating the impact of work stress parameters on AF onset show conflicting results. Researchers have reported the impact of AF on cognitive decline and on health-related quality of life, and have highlighted the role of interoceptive cues in the development of AF symptom burden and gender differences in psychological covariates of AF. Among biological pathways linking psychosocial factors to AF, research on autonomic regulation has yielded the most evidence so far, showing that the onset of AF is associated with simultaneous sympatho-vagal activation rather than an increase in vagal or sympathetic drive alone. Thus, modulation of the autonomic nervous system is likely to be a promising strategy for protecting the myocardium from pro-arrhythmic autonomic influences. Summary In total, the findings show that AF is embedded as a disease condition in a psycho-societal context and is not an isolated medical problem per se. A broader perspective than a focus on the electrophysiology alone is urgently needed. Keywords Atrial fibrillation . Psychosocial stress . Cognition . Dementia . Symptom perception . Depression . Anxiety . PTSD . Autonomic regulation
Seryan Atasoy and Hamimatunnisa Johar shared last authorship This article is part of the Topical Collection on Psychological Aspects of Cardiovascular Diseases * Karl-Heinz Ladwig [email protected]
2
Institute of Epidemiology, Mental Health Research Unit, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany
Andreas Goette [email protected]
3
German Centre for Cardiovascular Research (DZHK), Partner site Munich Heart Alliance, Munich, Germany
Seryan Atasoy [email protected]
4
St. Vincenz-Krankenhaus GmbH, Medizinischen Klinik II, Paderborn, Germany
5
Working Group on Molecular Electrophysiology, University Hospital Magdeburg, Magdeburg, Germany
6
Department of Psychosomatic Medicine and Psychotherapy, University of Gießen and Marburg, Marburg, Germany
Hamimatunnisa Johar [email protected] 1
Department of Psychosomatic Medicine and Psychotherapy, Klinikum rechts der Isar, Technische Universität München (TUM), Langerstr. 3, 81675 Munic
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