2018 Delayed enhancement and edema sequences accurately identifies acute myocardial infarction
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BioMed Central
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Meeting abstract
2018 Delayed enhancement and edema sequences accurately identifies acute myocardial infarction Chiara Lanzillo*, Mauro Di Roma, Cinzia Razzini, Marco Di Luozzo, Andrea Romagnoli, Massimiliano Sperandio, Noemi Terribili, Alessia D'Eliseo, Giovanni Simonetti and Francesco Romeo Address: Policlinico Tor Vergata, Rome, Italy * Corresponding author
from 11th Annual SCMR Scientific Sessions Los Angeles, CA, USA. 1–3 February 2008 Published: 22 October 2008 Journal of Cardiovascular Magnetic Resonance 2008, 10(Suppl 1):A287
doi:10.1186/1532-429X-10-S1-A287
Abstracts of the 11th Annual SCMR Scientific Sessions - 2008
Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1532-429X-10-S1-info.pdfThis abstract is available from: http://jcmr-online.com/content/10/S1/A287 © 2008 Lanzillo et al; licensee BioMed Central Ltd.
Background Cardiac magnetic resonance imaging (CMR) is frequently used to detect and quantify the size of myocardial infarction. Since no signal intensity difference of the enhanced region is observed between acute myocardial necrosis (AMN) and chronic myocardial necrosis (CMN), edema has been proposed for identification of myocardium at risk. The aim of the current study was to analyze the diagnostic accuracy of CMR to differentiate between AMN and CMN using edema T2w sequences, hypoperfusion on first-pass enhancement (FPE), delayed enhancement (DE) and wall thinning on cine in patients within acute coronary syndrome (ACS).
sequence acquired 10 minutes after gadolinium injection. Figure 1.
Results See Table 1
Conclusion T2w and DE-CMR enables accurate differentiation between AMN and CMN and territory identification of infarct-related artery. Edema indicates a recent infarction with a high successful of functional recovery, absence of transmural infarction identify viable myocardium.
Methods We examined 10 prospective ACS patients with history of CMN (8 male, 2 female, mean age 59 ± 11 years) by CMR [1.5 Tesla Philips Gyroscan Philips Medical System, Best, Netherlands] within three days of acute event (NSTEMI). We assessed left ventricular function by a steady-state free precession sequences, edema by a T2w black blood turbo spin echo fat suppressed sequence and first-pass perfusion by fast field echo T1w sequences during gadolinium injection. Visualization of myocardial necrosis was performed with inversion recovery turbo field echo T1 weighted
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Journal of Cardiovascular Magnetic Resonance 2008, 10(Suppl 1):A287
http://jcmr-online.com/content/10/S1/A287
Figure 1
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Journal of Cardiovascular Magnetic Resonance 2008, 10(Suppl 1):A287
http://jcmr-online.com/content/10/S1/A287
Table 1:
Parameter AMN
Sensitivity %
Specificity %
Positive predictive value %
Negative predictive value %
Edema Hypoperfusion Hypokinesia DE
100 67 78 100
100 50 100 75
100 6
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