2.8 In Patients with Isolated Ambulatory Hypertension Central Blood Pressure and Augmentation Index are Increased: the V
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High Blood Press Cardiovasc Prev 2008; 15 (3): 171-215 1120-9879/08/0003-0171/$48.00/0 © 2008 Adis Data Information BV. All rights reserved.
Blood Pressure Monitoring 2.8 In Patients with Isolated Ambulatory Hypertension Central Blood Pressure and Augmentation Index are Increased: the VOBARNO Study A. Paini (1), ML. Muiesan (1), M. Salvetti (1), E. Belotti (1), G. Galbassini (1), C. Agabiti-Rosei (1), C. Aggiusti (1), L. Micheletti (1), F. Marino (1), F. Bertacchini (1), E. Agabiti-Rosei (1) ` di Brescia, Brescia, Italy (1)Universita Introduction. Different blood pressure (BP) patterns have been identified by the use of both office and 24 hours BP measurement: sustained normotension (NT), isolated office hypertension (IOH), isolated ambulatory hypertension (IAH) and hypertension (HT). Pulse-wave analysis (PWA) has been proposed for non-invasive evaluation of central BP; furthermore, the derived ‘augmentation index’ (AIx) is an accepted indirect index of arterial stiffness. Aim. To assess the relationships between PWA measures and BP patterns in a general population sample in Northern Italy. Methods. In 242 untreated subjects (age 54.0±8.6 years, BMI 25.3±4.0, 47% males) radial artery applanation tonometry and PWA were used to derive central aortic pressures and AIx. All subjects underwent laboratory examinations and both clinic and 24 h BP measurement. Subjects were divided into subgroups: NT (office BP125/80 mmHg). Results. Patients with IAH and HT were older than NT(59.5± 8.4 and 55.3± 9.3 vs 51.1±6.4 years, respectively, p
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