58th Annual Symposium of the International Society for Clinical Electrophysiology of Vision (ISCEV 2020)
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ABSTRACTS
58th Annual Symposium of the International Society for Clinical Electrophysiology of Vision (ISCEV 2020) 14–16 September 2020
Springer-Verlag GmbH Germany, part of Springer Nature 2020 Foreword Welcome to the Special Meeting Issue of Documenta Ophthalmologica for the ISCEV 2020 Symposium. Though we are unable to assemble in person this year, the meeting organizers have assembled an informative program of presentations which reflect the depth and breadth of the international community dedicated to clinical electrophysiology of vision. The Abstract Editing Committee has made every effort to optimize the abstracts for clarity and readability—we have made no attempts to address questions of scientific or medical validity. This year, as it is not possible to address follow-up questions to the presenters face-to-face, we have included the email address of the corresponding author with each abstract to facilitate such communication. Enjoy the meeting! Abstract Editing Committee: Scott E. Brodie, Chair, Mitchell Brigell, Mary Johnson, Jonathan Lyons, Anne Moskowitz, Richard Smith
Oral Session 1: Pediatric electrophysiology O1.1 The role of visual electrodiagnostics in clinical evaluation of children with neurofibromatosis type 1 Tekavcˇicˇ Pompe, Manca1, Sˇusˇtar, Maja1
monocular stimulation was performed. All children had neuroimaging (brain MRI) where visual pathway gliomas were searched for, however in two of the children MRI was performed after visual electrodiagnostic evaluation. Results 16/35 (46%) children have documented optic pathway glioma with MRI. In 9/16 (56%) children with confirmed glioma, VEP was abnormal and correlated with MRI findings. In 6/19 (32%) children with documented optic pathway glioma, VEP was within normal limits, while one child couldn’t perform reliable visual electrodiagnostic testing. In 19/35 (54%) children optic pathway glioma was not detected by MRI. Among these children, four (21%) had abnormal VEP responses. In five children, neuroimaging was performed after visual electrodiagnostic evaluation had shown abnormal responses. In one child an optic pathway glioma was confirmed. Conclusion Visual electrodiagnostic tests have an important role in clinical evaluation of children with NF1. In cases with confirmed optic pathway glioma, normal VEP responses might imply intact visual pathway function. In cases where MRI testing was not yet performed, abnormal VEP responses imply the need for further neuroimaging of the visual pathway. Conflict of interest: None Funding: None Award applications: None Corresponding author email: manca.tekavcic-pompe@ guest.arnes.si
University Eye Clinic, Ljubljana, Slovenia Purpose To evaluate visual electrodiagnostic findings in children with neurofibromatosis type 1 (NF1) with or without optic pathway glioma. Methods 35 children (21 boys and 14 girls, age 4–18 years) with genetically confirmed NF1 were included. As part of ophthalmic workup, all children had visual electrodiagnostic testing, which included pattern ERG and pattern reversal VEP to f
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